Histopathological Characteristics of Mediastinal Tumors through 11 Years

Histopathological Characteristics of Mediastinal Tumors through 11 Years

Author(s)

Muneera Al-Khalifa, Sara Alsaad, Aishah Al-Kulaib, Muzoon Al-Muawda, Habib Al-Tareef, Abdulla Darwish,

Abstract

Background:

Mediastinal masses are rare. However, masses that grow in the confined space of the mediastinum can be life-threatening because they involve many important structures.

Objective:

 To evaluate the epidemiological and histopathological characteristics of mediastinal masses over 11 years.

Design:

A Retrospective Observational Study.

Setting:

 Cardiac Center, Bahrain Defence Force − Royal Medical Services Hospital (BDF-RMS), Bahrain.

Method:

All patients who underwent surgical resection of a mediastinal mass from January 2007 to December 2017 were included in the study. Patients’ personal characteristics and histopathological data were analyzed.

Result:

 Fifty-five patients underwent surgical resection of a mediastinal mass through 11 years; 38 (69.1%) were in the anterior mediastinum, 9 (16.4%) were in the middle mediastinum and 8 (14.5%) were in the posterior mediastinum. Thirty-one (56.4%) were males and 24 (43.6%) were females; the mean age was 46.6 years. Nineteen (34.5%) were non-neoplastic lesions and 36 (65.5%) were neoplastic lesions. Ten (18.2%) tumors were benign while 26 (47.3%) were malignant; 13 (23.6%) were primary and 13 (23.6%) were metastatic.

Conclusion:

In this study, the majority of the mediastinal masses occurred in the anterior mediastinum. Complete resection of these masses can be curative in most cases.

Bahrain Medical Bulletin

Bahrain Med Bull 2020; 42 (1): 13 – 19

(Available on: https://www.bahrainmedicalbulletin.com/MARCH2020/MAR2020_ABSTRACT/MAR2020_ABSTRACT_HISTOPATHOLOGICAL.pdf)